Page 9 - Boca Exposure - January '22

Boca Exposure, Page 9
Clostridia Difficile Colitis Treatment Pills On The Horizon

By Steven E. Reznick, abdominal pain and diarrhea, sometimes grossly bloody Interestingly, when the stool of all the disease victims was
M.D., FACP would consent to an enema of collected stool points out looked at for normal bacteria that is supposed to be present
Antibiotic related colitis just how miserable this entity makes the poor suffering in our bowels, they had a paucity of bacterial types expected.
powered by post antibiotic individuals. One week after taking the freeze-dried pill the numbers and
Clostridium difficile bacterial At a virtual meeting of the American College of diversity of healthy bacteria had increased due to the CP101
infection has become Gastroenterology 2021, Jessica Allegreti, M.D., M.P.H., a contents.
epidemic. Patients suffer gastroenterologist at the Brigham and Women’s Hospital The pill is made by Finch Therapeutics and now moves
from abdominal cramps, in Boston, Mass., reported on the most recent successful into Phase 3 studies prior to being ready to be presented for
fever, recurrent loose and trial of a freeze-dried human stool pill. The pill contains marketing. Competing firm Vedanta Biosciences is doing
bloody stools. Dehydration a powder of freeze-dried human stools from pre-selected similar studies with its whole stool VE303 pill while Seres
and even bowel perforation donors. The study selected patients who had suffered Therapeutics works with SER-109 which is an accumulation
have occurred. Treatment through several bouts of C. difficile colitis and were now of highly purified Firmicutes spores.
involves using a non-absorbable antibiotic called vancomycin. symptom free. The group had either been treated for their Having an oral pill to replenish our natural microbiome
If that failed, fidaxomicin has been used in recent years – since last recurrence with vancomycin or fidaxomicin. after an unfortunate antibiotic related colitis infection with C.
its development and approval. After a period of days for the antibiotics to wash out difficile will be a major advance in its treatment. Hopefully
Despite the use of these drugs, patients have been of their system, they were either assigned to receive the it will reduce the recurrences of this miserable disease.
having more frequent recurrences which sometimes CP101 pill or a placebo. Normally these patients would be Dr. Reznick is board certified in internal medicine,
require additional treatment. When these treatments told to resume their lives and receive no treatment unless with added qualifications in geriatrics. To schedule a
fail to stop recurrences, researchers have gone to fecal they developed symptoms of a C. difficile recurrence. The complimentary meeting with Reznick to discuss his
transplants – tried via collected stool enemas. The idea pill was more successful than the placebo in preventing personalized care concierge practice, call (561) 368-0191
that an individual suffering from fevers, severe recurrent recurrences at the 24-week mark. or visit www.BocaConciergeDoc.com.

The Fuller Center’s Annual Wee Dream Ball from page 8 success and lifelong learning. For school-age youth, we
have opened a private CHOICE elementary school serving
Sandra and Marvin Rubin, Rubin Obstgarten Family kindergarten to third grade, and we offer after-school,
Foundation, Linda and Robert Schmier, The Sam and Simone summer camp, and out-of-school-time programs to develop
Spiegel Family Foundation, Sokol Foundation and Peg skills in social interaction, literacy, science, technology,
Anderson, Eda and Cliff Viner, Gail Wasserman, Tina and math, and the arts, and providing tutoring, mentoring, and
John Westine, and Denise Zimmerman. enrichment activities. We have incorporated a teen program
To support the Fuller Center, please contact Director of providing youth the opportunities to build skills in leadership,
Advancement Mary Coleman at (561) 706-3357, Ext. 123 communication, project development, work skills readiness,
or email mcoleman@ffcdc.org. and community service.
About The Fuller Center At the Fuller Center, we believe that educated children and
The Fuller Center has been a community cornerstone for empowered families create a strong, supportive community.
over 50 years, providing under-resourced children the same The Fuller Center offers a unique, comprehensive system
educational opportunities as their more affluent peers. Our of family support to ensure that parents and caregivers are
goal is to support hardworking families and their children empowered to provide for their families and make a positive
to achieve their full potential. We believe all children should economic impact in our community. We know that when it
have the chance to experience success in school, in work, comes to turning the tide of generational, economic inequity
and in life, regardless of their parents’ income or ZIP code. and making a positive impact, tomorrow begins today! Top: Dana Weiss, Lauren Johnson, Megan Escamilla, Heidi
For children 6 weeks to 5 years old, we offer a holistic Facebook: @florencefullercenters Johnson Adams, Peggy Henry Van Dorp; Bottom: Carrie
early education program, setting the foundation for school Instagram: @florencefullercenters Rubin, Kathy Adkins, Denise Zimmerman